内脏脂肪组织用于预测严重的急性胰腺炎
Sumaswi Angadi1, Sukanya Bhrugumalla1, Ravichandra Nuggahalli Siddegowda1
1Department of Medical Gastroenterology, Nizam's Institute of Medical Sciences, Hyderabad, Telangana, India.
The Indian journal of medical research
|October 9, 2024
概括
在严重的急性胰腺炎 (AP) 病例中,内脏脂肪组织 (VAT) 面积显著增加. 这一发现表明,增值税可能是AP严重性的一个有价值的预测指标,特别是随着肥胖率的上升.
科学领域:
- 胃肠病学 胃肠病学
- 代谢障碍 代谢障碍 代谢障碍
- 医疗成像医学成像
背景情况:
- 急性胰腺炎 (AP) 是住院的常见胃肠道原因.
- 肥胖与AP严重程度增加,局部并发症,器官衰竭和死亡率有关.
- 以内脏脂肪组织 (VAT) 面积来衡量的内脏脂肪度可能是严重AP的优越预测因素,而不是BMI.
研究的目的:
- 评估内脏脂肪和急性胰腺炎的严重程度之间的关联.
- 评估测量内脏脂肪组织 (VAT) 面积在预测AP严重性的有用性.
主要方法:
- 一个单一中心的前性研究,涉及连续入院的AP患者.
- 在接收后48至72小时内测量内脏脂肪组织 (VAT) 面积.
- 增值税领域和AP严重程度 (轻度,中度,严重) 之间的相关性分析.
主要成果:
- 包括74名患有AP的患者.
- 与轻度/中度AP (115.11±29.85厘米2) 相比,重度AP (141.01±33.75厘米2) 的患者的平均增值税面积显著更大.
- 在预测严重的AP时,VAT的灵敏度为78.4%,特异性为54.1%,AUROC为0.722.
结论:
- 在增加内脏脂肪组织 (VAT) 和严重急性胰腺炎 (AP) 之间存在显著的关联.
- 增值税领域显示出作为预测AP严重性的预测预测指数的潜力.
- 鉴于全球肥胖趋势,需要进一步的研究来探索将增值税测量纳入AP预测指数的整合.
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