肺结节计算机辅助检测系统在标准剂量和低剂量儿科CT扫描上的表现:个体内比较
Russell C Hardie1, Andrew T Trout2,3,4, Jonathan R Dillman2,3
1Department of Electrical and Computer Engineering, University of Dayton, 300 College Park, Dayton, OH 45469.
AJR. American journal of roentgenology
|October 9, 2024
概括
与标准剂量扫描相比,计算机辅助检测 (CAD) 系统在低剂量CT扫描上对儿科肺结节的敏感性较低. 对较小的结节而言,性能降低更为显著,因此在小儿低剂量CT协议中使用这些系统时需要谨慎.
科学领域:
- 放射学和成像学 放射学和成像学
- 人工智能在医学中的应用
- 儿科肺病学 儿科肺病学
背景情况:
- 肺结节的计算机辅助检测 (CAD) 系统可能会因为图像噪声增加而在低剂量儿科CT扫描上表现下降.
- 成人培训的CAD系统越来越多地应用于儿科成像,这引发了关于它们在不同剂量水平的有效性的问题.
研究的目的:
- 为了在同一个患者中比较在低剂量和标准剂量儿科胸部CT扫描之间检测肺结节的成年人数据上训练的两个CAD系统的性能.
- 评估图像噪声对儿科患者CAD系统敏感性的影响.
主要方法:
- 对73名接受标准剂量和低剂量胸部CT扫描的儿科患者进行了回顾性分析.
- 两种公开可用的CAD系统 (FlyerScan和MONAI),经过成人数据的训练,被用于分析结节 (3-30毫米).
- 对于每个系统,在固定的错误阳性率下计算灵敏度,比较剂量级别之间的性能.
主要成果:
- 与标准剂量扫描相比,这两种CAD系统在低剂量扫描上都表现出降低的灵敏度.
- 飞行器扫描灵敏度从76.9% (标准剂量) 降至66.8% (低剂量);MONAI灵敏度从67.6%降至62.3%.
- 在小于5毫米的结核中,检测的减少更为明显.
结论:
- 使用成年人训练有素的CAD系统检测儿科肺结节在低剂量CT扫描上敏感度较低.
- 这些发现强调了在低剂量儿科CT协议中应用这些CAD系统时需要谨慎,特别是对于小结体.
- 可能需要进一步的研究来优化用于儿科低剂量成像的CAD算法.
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