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Updated: Apr 13, 2026

A 96 Well Microtiter Plate-based Method for Monitoring Formation and Antifungal Susceptibility Testing of Candida albicans Biofilms
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抗真菌敏感性测试和Candida auris菌株菌群分析

Gulsah E Ozmerdiven, Arzu Irvem, Zeynep Cizmeci

    Clinical laboratory
    |October 9, 2024
    PubMed
    概括

    这项研究发现,Candida auris分离物中对可纳和安波特里辛B的耐药性很高. 所有菌株都属于南亚第1类,对弱势患者构成威胁.

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    Amphotericin B is a broad-spectrum antifungal agent that exploits structural differences between fungal and mammalian cell membranes. Its amphipathic structure—featuring a hydrophobic polyene-lactone ring and a hydrophilic region containing mycosamine and carboxylic acid groups—enables selective binding to ergosterol, a sterol predominantly found in fungal plasma membranes. This selective interaction underlies the drug’s antifungal activity, although weak binding to...
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