健康成年人动脉硬的年龄相关变化:来自韩国大型队列研究的见解
Hyun-Jin Kim1, Jeong-Hun Shin1, Byung Sik Kim1
1Division of Cardiology, Department of Internal Medicine, Hanyang University College of Medicine, Hanyang University Guri Hospital, Guri, South Korea.
Atherosclerosis
|October 9, 2024
概括
在健康的成年人中,动脉硬度随着年龄的增长而增加,男性在50岁以后出现更为急剧的升高. 这项研究追踪了不同年龄组的动脉硬度 (baPWV) 的年度变化.
科学领域:
- 心血管健康 心血管健康
- 衰老研究研究 衰老研究
- 血管生物学 血管生物学
背景情况:
- 动脉硬是与衰老和动脉硬化有关的心血管风险因素.
- 这项研究侧重于没有先前存在心血管疾病的健康个体.
研究的目的:
- 为了研究与年龄相关的动脉硬度的年度变化.
- 在一大批健康的韩国成年人中分析这些变化.
主要方法:
- 利用了来自30-79岁的195,405名韩国成年人的数据 (2006-2019).
- 通过腕脉冲波速度 (baPWV) 评估动脉硬度.
- 在147313名参与者中分析了baPWV (ΔbaPWV) 的年度变化.
主要成果:
- 腕脉冲波速度 (baPWV) 在两性中随着年龄的增长而逐渐增加.
- 男性的baPWV年均呈现一致的增加,而女性的baPWV在50岁以后显著上升.
- 在男性 (70-79岁) 和女性 (50-60岁) 中,在baPWV中观察到与年龄相关的更大传播.
结论:
- 在健康人群中,动脉硬会随着年龄的增长而进展.
- 在动脉硬性进展的速度和模式上存在显著的基于性别的差异.
- 研究结果强调了年龄和性别在血管健康监测中的重要性.
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