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Updated: Jun 11, 2025

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通过调节Grk5表达,Irg1调节骨质稳定

Xuewu Sun1, Boya Zhang2, Putao Yuan3

  • 1Department of Orthopaedic, Sir Run Run Shaw Hospital, Zhejiang University School of Medicine, Hangzhou, China; Key Laboratory of Musculoskeletal System Degeneration and Regeneration Translational Research of Zhejiang Province, Hangzhou, China; Key Laboratory of Biotherapy of Zhejiang Province, Hangzhou, China.

Biochemical and biophysical research communications
|October 9, 2024
PubMed
概括

线粒体伊塔康酸盐生产酶Irg1的缺乏通过Grk5信号增强了骨质细胞分化. 这表明骨疾病的潜在治疗点,尽管生理骨平衡在很大程度上不受影响.

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