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Updated: Jun 11, 2025

Using an Extracellular Flux Analyzer to Measure Changes in Glycolysis and Oxidative Phosphorylation during Mouse Sperm Capacitation
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重新构想马精子保护:通过酸盐诱导的华堡效应来打击碳毒性,以增强精子的寿命和功能

Fernando J Peña1, Francisco Eduardo Martín-Cano1, Laura Becerro-Rey1

  • 1Laboratory of Equine Reproduction and Equine Spermatology, Veterinary Teaching Hospital, Universidad de Extremadura, Cáceres, Spain.

Journal of equine veterinary science
|October 9, 2024
PubMed
概括

马的精子主要使用线粒体作为能量,但扩展器经常使用多余的葡萄糖. 这篇评论强调了这种"碳化合物毒性"在保存期间对精子健康的潜在危害.

关键词:
有氧糖溶解是有氧的.葡萄糖是一种葡萄糖.代谢过程中的代谢.铁酸盐是什么 铁酸盐是什么精子动物 (Spermatozoa) 是一种精子.马的马匹 马的马匹

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Fates of Pyruvate01:20

Fates of Pyruvate

Pyruvate is the end product of glycolysis, where glucose is oxidized to pyruvate, simultaneously reducing NAD+ to NADH. Two molecules of ATP are also produced by substrate-level phosphorylation.
In aerobic organisms, pyruvate is metabolized via the citric acid cycle to produce reduced coenzymes NADH and FADH2. These coenzymes are then oxidized in the electron transport chain to produce ATP and, in the process, regenerate the NAD+ and FAD. As seen in some cell types and organisms, fermentation...
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