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使用扩散光学眼镜镜片控制近视:多中心随机对照,疗效和安全性研究 (CYPRESS) 的4年结果
Deborah Laughton1, Jennifer S Hill2, Marcella McParland2
1SightGlass Vision Inc, Dallas, Texas, USA dlaughton@sightglassvision.com.
BMJ open ophthalmology
|October 9, 2024
概括
扩散光学技术 (DOT) 眼镜镜片有效地减缓了四年内儿童近视的进展. 这些DOT 0.2镜头对于控制年轻人的近视是安全和有益的.
科学领域:
- 眼科医生 眼科 眼科
- 儿科光学测量 儿科光学测量
- 近视控制研究近视研究
背景情况:
- 近视是儿童日益严重的公共卫生问题.
- 有效的近视控制策略对于预防长期的眼部并发症至关重要.
研究的目的:
- 评估扩散光学技术 (DOT) 眼镜镜片对儿童近视控制的4年疗效.
- 评估DOT镜片在减少轴长和折射误差进展方面的安全性和有效性.
主要方法:
- 一项为期四年的多中心,随机,受控试验 (CYPRESS部分1和2) 涉及256名6-10岁儿童.
- 两个DOT镜头设计 (测试1,测试2) 与标准单视控制镜头的比较.
- 同主终点:轴长度 (AL) 的变化和循环球相等折射率 (cSER).
主要成果:
- 与对照镜头相比,DOT Test 1镜头在研究的两个部分都显示了AL和cSER在统计学上显著的减少.
- 第一部分: -0.13mm AL和0.33D cSER差异;第二部分: -0.05mm AL和0.13D cSER差异.
- 在2年和3年,COVID-19限制似乎对治疗疗效产生了负面影响.
结论:
- 在4年内,DOT 0.2眼镜镜头在减缓近视的进展方面显示出安全性和有效性.
- 结果支持了减少视网膜对比度可以抑制儿童近视进展的理论.
- COVID-19 流行病可能影响了治疗结果,突出了持续遵守治疗的必要性.
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