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支气管切除症的流行病学
Mattia Nigro1,2, Irena F Laska3, Letizia Traversi4
1Department of Biomedical Sciences, Humanitas University, Milan, Italy mattia.nigro@humanitas.it.
概括
支气管病是一种慢性呼吸道疾病,其全球发病率和流行率呈上升趋势. 本综述检查了现实世界关于其流行病学,死亡率和医疗负担的数据,突出了地理差异.
科学领域:
- 肺部病理学 肺部病理学
- 流行病学 流行病学
- 公共卫生 公共卫生
背景情况:
- 支气管切除症是一种慢性呼吸道疾病,以不可逆转的气道扩大为标志,导致咳和唾液产生等症状.
- 全球支气管病的发病率和患病率正在上升,这可能是由于诊断和认识的改善,医疗保健成本的增加和患者死亡率的增加.
- 报告的患病率差异很大 (每10万人中有52.3到>1000),方法上的缺陷和地理因素有助于数据异质性.
研究的目的:
- 为了提供一个全面的概述,目前的现实世界流行病学数据,支气管病.
- 分析全球的发病率,流行率,死亡率和医疗负担.
- 探索支气管病变决定因素的地理差异及其对流行病学的影响.
主要方法:
- 系统审查可用的真实世界关于支气管病变的流行病学数据.
- 对报告发病率,流行率和死亡率的研究进行分析.
- 检查影响疾病流行病学地理差异的因素.
主要成果:
- 全球支气管病发病率数据存在显著的异质性,这可能是由于方法上的不一致性和不同的评估方法.
- 支气管切除症队伍的死亡率在4-5年内从16-24.8%不等,地理差异受病因,并发症和获得护理的影响.
- 在某些地区,有限的医疗保健机会导致诊断不足,疾病严重程度增加和死亡率增加.
结论:
- 准确的全球支气管病流行病学需要标准化的评估方法来克服当前数据的异质性.
- 解决病因学,微生物学和医疗保健准入方面的地理差异对于管理支气管病的负担和改善患者的治疗结果至关重要.
- 对区域决定因素的进一步研究对于有针对性的公共卫生干预和改善全球患者护理至关重要.
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