人工智能驱动的胸部计算机断层扫描分析揭示了流行血液透析患者中COVID-19死亡率的预后见解
Eunji Kim1,2, Soo-Jin Yoon3, Sungbong Yu4
1Department of Internal Medicine, Kangnam Sacred Heart Hospital, Hallym University College of Medicine, Seoul, Republic of Korea.
Kidney research and clinical practice
|October 9, 2024
概括
胸部CT扫描显示了COVID-19肺炎血液透析患者死亡率的关键指标. 诸如肺部卷入和肺部溢出等发现显著预测了结果,即使疾病最小.
科学领域:
- 放射学 放射学是一门学科.
- 腎臟病學 (nephrology) 是一種醫學專業.
- 传染性疾病 传染性疾病
背景情况:
- 新型冠状病毒疾病2019 (COVID-19) 已导致全球死亡率,但对末期病患者的结果尚不清楚.
- 这项研究侧重于常见的血液透析患者,这是一个不清楚COVID-19预后的脆弱人群.
研究的目的:
- 评估胸部计算机断层扫描 (CT) 发现在预测COVID-19相关死亡率中的预后价值.
- 评估人工智能 (AI) 辅助CT分析在量化肺部参与方面的实用性.
主要方法:
- 对326名患有COVID-19的常见血液透析患者进行回顾性分析,这些患者接受了胸部CT.
- 评估CT特征,包括多叶膜溢出,肺体积,巩固,透和地面玻璃不透明.
- 后勤回归分析以确定CT发现与住院死亡率之间的关联.
主要成果:
- 多变量分析确定了肺部参与率>2.7% (OR,16.70),肺部溢出 (OR,3.28),结节凝固 (OR,4.08) 和不整的透 (OR,3.75) 作为显著的死亡风险因素.
- 患者中有21点5% (70/326) 患者死亡.
- 人工智能辅助CT分析有效量化了肺部感染,突出了其与死亡率的关联.
结论:
- 特定的胸部CT发现,包括肺部参与>2.7%,肺部溢出,结节巩固和不整的透,是COVID-19肺炎血液透析患者死亡率的重要预测因素.
- 人工智能辅助CT分析对于评估肺部感染程度及其与死亡风险增加的相关性是有价值的.
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