在神经性膀的儿科患者中检测结石病的尿路透镜检查:一个单一机构的病例控制研究
Yashaswi Parikh1, Sami Shaikh1, Aznive Aghababian1
1Division of Urology, Children's Hospital of Philadelphia, 3401 Civic Center Blvd, Philadelphia, PA, USA.
Journal of pediatric urology
|October 9, 2024
概括
尿路透镜 (URS) 对于患有神经性膀 (NGB) 的儿科患者来说是安全的,尽管石头负担和感染风险更高. 谨慎的抗生素管理对于这些接受URS治疗尿病的患者至关重要.
科学领域:
- 儿科泌尿外科 儿科泌尿外科
- 内分泌病学 在内分泌病学.
- 腎臟病學 (nephrology) 是一種醫學.
背景情况:
- 尿道透视 (URS) 对于儿科尿病提出了挑战,特别是在患有神经性膀 (NGB) 和/或非行走状态的患者中.
- 这些患者表现出更高的并发症率,增加了结石形成/复发的风险,以及更容易感染和术后并发症.
研究的目的:
- 评估URS在患有NGB和/或非健行状态的儿科患者的结果.
- 将这些结果与没有这些并发症的儿科患者的对照组进行比较.
主要方法:
- 一个回顾性分析的未来单一机构注册的儿科患者 (<18岁) 接受URS石病 (七月2012年-7月2021年).
- 患者被分为两组:NGB患者 (有或没有非行走状态) 和对照组.
- 基线人口统计数据,手术前成像,手术内细节和手术后30天结果的比较.
主要成果:
- 与对照组 (2石,9毫米) 相比,NGB患者的石头负担更高 (3石,15毫米).
- NGB患者经历了更长的手术 (86分 vs 60分钟),增加了分阶段手术的需要,更长的住院时间 (1天 vs 0天),以及延长了手术前抗生素的使用.
- 虽然整体30天的并发症相似,但NGB患者在一年内患有更高的发烧性尿路感染 (8.2%对1.3%) 和复发性ipsilateral URS率 (34.6%对18.9%).
结论:
- URS是对患有NGB的儿童尿病的安全有效治疗方法.
- 感染性并发症的风险增加,需要对接受URS的NGB患者进行细致的术前和术后抗生素管理.
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