高风险儿科药物:通过跨学科共识技术的列表提案
Yolanda Hernández Gago1, Pedro J Alcalá Minagorre2, Belén Rodríguez Marrodán3
1Servicio de Farmacia, Complejo Hospitalario Universitario Insular Materno-Infantil, Las Palmas de Gran Canaria, España.
概括
这项研究确定了两岁以上住院儿童的高风险药物 (HRM). 在24个类别中100种药物的共识清单有助于提高儿科患者的安全性.
科学领域:
- 儿科药理学 儿科药理学
- 药物安全 药物安全
- 医院药房实践 医院药房实践
背景情况:
- 儿科患者面临更高的药物错误和伤害的风险.
- 识别高风险药物 (HRM) 对于提高安全性的战略至关重要.
- 特殊的人群,比如体重过重的儿童,需要集中注意力.
研究的目的:
- 创建一个更新的,操作的HRM名单,用于医院使用在两岁以上的儿童.
- 通过一组跨学科的儿科医生和医院药剂师达成共识.
- 支持西班牙医院药剂师协会和西班牙儿科医院医学协会之间的合作努力.
主要方法:
- 采用了两阶段的方法:对初步清单进行文献综述和达成共识的双轮Delphi方法.
- 该研究涉及37名专家,其中32人 (86.4%) 完成了两轮Delphi.
- 结果使用偶然协议概率和修改的卡帕统计数据进行了验证.
主要成果:
- 最初的审查确定了26种药理类和96种药物.
- 最终的共识清单包括24个药理类和100个HRM.
- 参与者之间达成了高水平的同意 (94.9%通过修改的卡帕统计数据).
结论:
- 编制的清单是未来研究和干预的宝贵工具.
- 它旨在提高一般儿科患者的药物安全性.
- 该清单特别适用于高风险的儿科亚组,包括体重过重的儿童.
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