在免疫功能低下的疾病中侵袭性真菌感染:强调COVID-19
Mahaldeep Kaur1, Payal Thakur1, Nandini Verma1
1MTCC and Gene Bank, CSIR-Institute of Microbial Technology, Sector 39A, Chandigarh, India.
Current microbiology
|October 9, 2024
概括
侵入性真菌共同感染,特别是粘菌菌,显著增加了COVID-19死亡率. 在免疫功能低下的患者中,这些真菌感染的早期诊断和管理至关重要.
科学领域:
- 医学真菌学 医学真菌学
- 传染性疾病 传染性疾病
- 关键护理医学 关键护理医学
背景情况:
- COVID-19大流行导致高死亡率,侵袭性真菌联合感染的贡献很大,特别是在重症患者中.
- 住院COVID-19患者的免疫功能障碍为Mucorales,Aspergillus和Candida等真菌病原体创造了易受影响的环境.
- 粘菌菌,阿斯伯吉洛症和角膜炎是关键的真菌共同感染,粘菌菌在印度很普遍.
研究的目的:
- 审查COVID-19患者侵入性真菌感染的流行病学,危险因素,诊断和治疗.
- 为了突出诊断这些共同感染的挑战,由于目前方法的局限性.
- 强调早期和准确诊断的重要性,以改善患者的治疗结果.
主要方法:
- 文献综述侧重于COVID-19患者的侵入性真菌感染.
- 对流行病学数据的分析和风险因素的预测.
- 讨论诊断挑战和治疗策略.
主要成果:
- 常见的真菌病原体包括Mucorales,Aspergillus和Candida物种.
- 危险因素包括不受控制的糖尿病,肺部疾病,中性质衰竭和类固醇治疗.
- 诊断仍然具有挑战性,影响及时管理和患者的结果.
结论:
- 侵入性真菌感染对COVID-19患者构成重大威胁,特别是免疫力低下者.
- 准确及时诊断对于有效管理和降低死亡率至关重要.
- 对改进诊断工具和治疗方案进行进一步的研究是有必要的.
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