HES1增强了高盐应激反应,作为NFAT5-DNA结合增强剂

Hiroki Ryuno1, Yusuke Hanafusa1, Takao Fujisawa1,2

  • 1Laboratory of Cell Signaling, Graduate School of Pharmaceutical Sciences, The University of Tokyo, Bunkyo-ku, Tokyo, Japan.

Communications biology
|October 9, 2024
PubMed
概括

高盐应激激活了激活T细胞的核因子5 (NFAT5). 毛发和增强分离-1 (HES1) 被确定为一个关键的调节器,促进NFAT5活性和细胞对透应激的保护.

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