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Updated: Jun 11, 2025

Next Generation Sequencing for the Detection of Actionable Mutations in Solid and Liquid Tumors
11:15

Next Generation Sequencing for the Detection of Actionable Mutations in Solid and Liquid Tumors

Published on: September 20, 2016

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超多重原发性肺癌在MAPK通路中存在高频BRAF和低频EGFR突变

Haochen Li1,2, Zhicheng Huang1, Chao Guo1

  • 1Department of Thoracic Surgery, Peking Union Medical College Hospital, Chinese Academy of Medical Sciences and Peking Union Medical College, Beijing, 100730, China.

NPJ precision oncology
|October 9, 2024
PubMed
概括

具有众多病变的多重原发性肺癌 (MPLC),称为超级MPLC,显示出不同的基因组模式. 与EGFR不同的是,高的BRAF突变率是这些侵袭性肺癌的特征,影响了治疗的有效性.

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