监督有氧训练对糖尿病老年患者脱脂症的影响
Ahmad H Alghadir1, Sami A Gabr1, Amir Iqbal2
1Department of Rehabilitation Sciences, College of Applied Medical Sciences, King Saud University, P.O. Box 10219, Riyadh, 11433, Saudi Arabia.
BMC endocrine disorders
|October 10, 2024
概括
六个月的适度有氧运动显著改善了糖尿病前期和2型糖尿病患者的血糖控制,脂质概况和减少炎症 (hs-CRP). 这种运动干预也提高了心肺呼吸能力 (VO2max),并对胰岛素抵抗产生了积极影响.
科学领域:
- 内分泌学和新陈代谢学
- 心血管健康 心血管健康
- 运动生理学 运动生理学
背景情况:
- 久坐不动的生活方式和体力活动不足与更高的糖尿病患病率和并发症有关.
- 这项研究调查了监督有氧训练对糖尿病前期和2型糖尿病 (T2DM) 的代谢和炎症标志物的影响.
研究的目的:
- 评估为期六个月的中等强度有氧训练计划对血清脂质概况,hs-CRP水平以及糖尿病前期和T2DM患者相关相关相关的效果.
- 评估血糖控制,胰岛素敏感性和心肺呼吸能力 (VO2max) 的改善.
主要方法:
- 一项比较性研究,采用双臂,并行组,测试前后测试设计.
- 50名参与者 (30-70岁) 患有T2DM (诊断超过5年) 被分为糖尿病前期 (HbA1c ≤6.5%) 和T2DM (HbA1c ≥6.5%) 组 (每组n=25).
- 干预包括六个月的中等强度监督有氧运动;测量包括血糖,HbA1c,胰岛素,脂质概况和hs-CRP在基线和干预后.
主要成果:
- 六个月的有氧训练显著降低了两个组的BMI,禁食血糖,HbA1c,hs-CRP和脂质参数 (T-Cholest,TG,LDL-C).
- 在胰岛素水平和胰岛素耐药性 (HOMA-IR) 中观察到显著改善,以及增强的VO2max,表明身体健康有所改善.
- 降低的hs-CRP,HOMA-IR和改善的脂质样本/胰岛素水平与HbA1c正相关,这表明这些标记物受到血糖控制和运动的影响.
结论:
- 在糖尿病前期和T2DM患者中,为期六个月的适度有氧训练对血糖控制,脂质概况产生积极影响,并减少炎症 (hs-CRP).
- 运动干预改善了心肺呼吸能力 (VO2max),并通过改善脂质不良,血糖控制和胰岛素耐药性,作为预防心血管疾病的保护调节剂.
- 定期运动,通过其抗炎作用和改善心肺呼吸能力,脂质样本,血糖和胰岛素抵抗,可以帮助减轻糖尿病前期和T2DM患者的心血管疾病风险.
相关概念视频
01:26Atherosclerosis III: Management
2
Management of atherosclerosis involves an integrated strategy encompassing pharmacological treatment, surgical interventions, lifestyle changes, and nutrition therapy to address the multifactorial nature of the disease.Pharmacological TherapyA cornerstone of atherosclerosis management is the use of pharmacological agents. Statins, such as atorvastatin, are pivotal in inhibiting HMG-CoA reductase, an enzyme that catalyzes an initial step in cholesterol synthesis in the liver. This reduction in...
2
01:26Coronary Artery Disease IV: Medical Management
4
Effective preventive measures for coronary artery disease (CAD) focus on controlling modifiable risk factors, including cholesterol abnormalities and lifestyle changes.Cholesterol ManagementFirst, the Mediterranean diet and the American Heart Association advocate for maintaining low-density lipoprotein (LDL) cholesterol levels below 100 mg/dL, with a more stringent recommendation of below 70 mg/dL for individuals at high risk. LDL cholesterol, often termed "bad cholesterol," can lead to the...
4
01:26Angina IV: Management
3
IntroductionThe management of angina requires a comprehensive approach that includes pharmacological therapies, medical procedures, and lifestyle modifications.Pharmacological TherapiesAntiplatelet agents, such as aspirin, clopidogrel, prasugrel, and ticagrelor, play a pivotal role in preventing thrombus formation in patients with angina. These medications inhibit platelet aggregation and reduce the likelihood of myocardial infarction and other cardiovascular events.Anticoagulants, including...
3
01:20Exercise and Cardiovascular Response
741
Exercise significantly impacts cardiovascular response, which is crucial for understanding patient health and designing effective treatment plans.
Light to moderate physical activity initiates a series of interconnected responses in the body. The heart rate modestly increases in anticipation of the workout, followed by widespread vasodilation as oxygen consumption by skeletal muscles increases. This results in decreased peripheral resistance, increased capillary blood flow, and accelerated...
Light to moderate physical activity initiates a series of interconnected responses in the body. The heart rate modestly increases in anticipation of the workout, followed by widespread vasodilation as oxygen consumption by skeletal muscles increases. This results in decreased peripheral resistance, increased capillary blood flow, and accelerated...
741
01:27Peripheral Artery Disease III: Interprofessional Care
3
Peripheral Artery Disease (PAD) is characterized by narrowed arteries that diminish blood flow to the extremities. Effective management of PAD requires an interprofessional approach involving various healthcare professionals. The critical aspects of interprofessional care for PAD patients focus on risk factor modification, drug therapy, exercise therapy, nutrition therapy, critical limb ischemia care, and interventional radiology and surgical procedures.The primary treatment goal for PAD...
3
01:23Atherosclerosis IV: Nursing Management
2
Nursing management for a patient with arteriosclerosis involves a comprehensive approach focusing on lifestyle modification, disease monitoring, education, and symptomatic care. Here is an overview of effective nursing strategies:Assessment and Monitoring: Initial and ongoing assessments are crucial. Nurses must document the patient's medical history, including any hypertension, diabetes, hyperlipidemia, and other cardiovascular diseases. Assessments also cover family history and lifestyle...
2