术前高级扩散磁共振成像的应用,用于评估低度质瘤的术后复发
Luyue Gao1,2, Yuanhao Li1, Hongquan Zhu1
1Department of Radiology, Tongji Hospital, Tongji Medical College, Huazhong University of Science and Technology, 1095 Jiefang Avenue, Wuhan, 430030, PR China.
概括
术前高级扩散MRI有效预测较低级别质瘤的复发. 轴外垂直扩散度 (De) 参数显示高精度,多参数模型达到0.96 AUC.
科学领域:
- 神经成像是一种神经成像.
- 在瘤学瘤学.
- 放射学 放射学是一门学科.
背景情况:
- 低度结质瘤 (LrGG) 经常复发,尽管进行了广泛的研究.
- 预测术后复发对于患者管理至关重要.
- 先进的扩散MRI (dMRI) 提供了非侵入性评估的潜力.
研究的目的:
- 评估手术前高级dMRI在预测LrGG在手术后两年内复发的疗效.
- 为了确定特定的dMRI参数,表明复发风险.
主要方法:
- 48名LrGG患者 (23例复发,25例不复发) 接受了高级的dMRI.
- 重建的dMRI模型包括AFD,WMTI,DTI,DKI,NODDI,宾汉NODDI和SMI.
- 正角局部最小平方-差异分析 (OPLS-DA) 构建了一个多参数预测模型.
主要成果:
- 在复发和非复发组之间,dMRI参数 (AFD,AWF,MD,MK,FA,ICVF,De,De,fw) 的显著差异.
- 轴突外垂直扩散性 (De) 显示出最高的AUC (0.885).
- 一个整合各种dMRI技术的多参数模型实现了0.96.6的AUC.
结论:
- 术前高级dMRI在评估LrGG术后复发方面非常有效.
- 来自标准模型成像 (SMI) 的De参数显示作为复发生物标志物具有前景.
相关概念视频
01:24Magnetic Resonance Imaging
7.6K
Magnetic resonance imaging (MRI) is a noninvasive medical imaging technique based on a phenomenon of nuclear physics discovered in the 1930s, in which matter exposed to magnetic fields and radio waves was found to emit radio signals. In 1970, a physician and researcher named Raymond Damadian noticed that malignant (cancerous) tissue gave off different signals than normal body tissue. He applied for a patent for the first MRI scanning device in clinical use by the early 1980s. The early MRI...
7.6K
01:27Imaging Studies IV: Magnetic Resonance Imaging
427
Introduction:Magnetic Resonance Imaging, or MRI, can include a specialized imaging technique of the urinary system known as Magnetic Resonance Urography (MRU). This radiation-free technique uses strong magnetic fields and radio waves to produce detailed images with the help of a computer. MRU is particularly effective for visualizing fluid-filled structures like the kidneys, ureters, and bladder.Applications of MRI in the Genitourinary SystemKidneys and Ureters: MRI detects tumors, cysts,...
427