输液反应与替代疗法在全国缺铁德克斯特兰期间的替代疗法
Brigid Jacob1, Maria Jamil1, Shahm Raslan1
1Henry Ford Health, Detroit, Michigan, USA.
European journal of haematology
|October 10, 2024
概括
全国缺铁右导致铁糖的使用增加,导致更多的输液反应,主要是轻微的. 经历反应的患者不太可能完成他们的铁输液计划.
科学领域:
- 血液学 血液学 血液学
- 药理学 药理学是指药理学的学科.
- 临床药房 临床药房
背景情况:
- 在2023年初全国短缺之前,铁右是该机构的主要静脉注射铁.
- 短缺需要使用替代铁配方,如铁糖和铁糖/糖.
- 这些替代品的患病率增加与观察到的铁输液反应的增加相关.
研究的目的:
- 评估国家铁短缺对静脉注射铁输液反应的影响.
- 分析与各种铁配方和剂量相关的输液反应.
- 为了比较患者在反应后遵守输液计划的情况.
主要方法:
- 从2022年7月到2023年6月,在三个诊所接受铁输液的880名患者的回顾性分析.
- 根据铁的配方,剂量和严重程度对74种输液反应进行分类和分析.
- 统计比较不同铁制品的反应速率和处理完成率.
主要成果:
- 铁糖糖,特别是500毫克剂量,最常与反应 (55.41%) 相关.
- 大多数观察到的反应 (83.7%) 是轻微的 (等级0或1).
- 经历反应的患者显着不太可能完成他们计划的输液,导致停止治疗.
结论:
- 由于缺乏铁,转向替代铁输注增加了输注反应的发生率.
- 高剂量的铁糖糖具有更高的反应风险,尽管大多数是温和的.
- 输液反应对治疗完成率产生负面影响,需要仔细的患者管理和配方选择.
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