在没有鼻息肉的慢性鼻炎患者中进行内镜鼻手术的正鼻和鼻后嗅觉功能
Paolo Boscolo-Rizzo1, Claire Hopkins2, Thomas Hummel3
1Department of Medical, Surgical and Health Sciences, Section of Otolaryngology, University of Trieste, Trieste, Italy.
International forum of allergy & rhinology
|October 10, 2024
概括
嗅觉功能障碍 (OD) 在没有鼻息肉 (CRSsNP) 的慢性鼻炎中很常见. 透视鼻手术 (ESS) 在37%的CRSsNP患者中改善了嗅觉,但整体OD患病率仍然相对较低.
科学领域:
- 耳鼻喉科 耳鼻喉科 耳鼻喉科
- 鼻科 鼻科是指鼻科的专家.
- 神经科学是一个神经科学.
背景情况:
- 嗅觉功能障碍 (OD) 是慢性鼻炎 (CRS) 的一个标志性症状.
- 没有鼻息肉的CRS (CRSsNP) 的OD比鼻息肉的CRS (CRSwNP) 了解得更少.
- 这项研究调查了在未经手术治疗的CRSsNP患者内镜鼻手术 (ESS) 后的OD患病率和变化.
研究的目的:
- 确定CRSsNP患者在ESS前后的嗅觉功能障碍的患病率.
- 评估ESS对CRSsNP的鼻腔和鼻后嗅觉功能的影响.
- 将CRSsNP中的OD流行率与CRSwNP中的发现进行比较.
主要方法:
- 一项前性研究涉及97名CRSsNP患者和97名健康对照.
- 在基线和ESS后6个月进行心理嗅觉测试 (嗅探棒,粉末香味).
- 评估正鼻和鼻后嗅觉功能.
主要成果:
- 在基线时,28.4%的CRSsNP患者有OD,而对照组只有8.6%.
- 在CRSsNP患者中,鼻后嗅觉功能明显较差.
- 在ESS后6个月,37.0%的CRSsNP患者表现出嗅觉功能显著改善,3.7%的嗅觉功能恶化.
结论:
- 虽然37%的CRSsNP患者在ESS后经历了改善的嗅觉,但该组的整体OD患病率低于CRSwNP.
- 在CRSsNP中,ESS显示了增强正鼻嗅觉的潜在益处.
- 在CRSsNP中ESS后,嗅觉功能的改善似乎有限.
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