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自闭症儿童的特异同步学生调节
Isabel H Bleimeister1,2, Inbar Avni2,3,4, Michael C Granovetter4
1Psychology Department, Ben Gurion University of the Negev, Beer Sheva, Israel.
概括
患有自闭症的儿童表现出比通常发育的儿童更可变的瞳孔反应. 这种瞳孔测量测量显示了自闭症中神经活动调节的差异.
科学领域:
- 神经科学是一个神经科学.
- 发展心理学 发展心理学
- 自闭症研究 自闭症研究
背景情况:
- 自闭症谱系障碍 (ASD) 的特点是神经处理的差异.
- 以前的研究表明,自闭症儿童的脑部反应和眼睛运动异常.
- 瞳孔测量为研究ASD神经调节提供了一种新的非侵入性方法.
研究的目的:
- 调查自闭症和没有自闭症的幼儿的瞳孔反应变异性.
- 为了确定瞳孔测量能否捕捉自闭症中特异性神经活动.
- 评估瞳孔测量对研究幼儿自闭症的有用性,包括那些有智力障碍的儿童.
主要方法:
- 从111名年龄在4.5岁左右的儿童 (74名患有自闭症) 中收集了瞳孔测量记录.
- 孩子们观看了三个90秒的电影,并分析了学生的时间课程.
- 学生反应的学科间相关性在组内和组之间计算 (自闭症与典型发育).
主要成果:
- 与典型发育的儿童相比,患有自闭症的儿童表现出明显较弱的学科间瞳孔反应相关性.
- 这些发现独立于凝视对象之间的相关性.
- 观察到的最大差异是对一部描绘社会互动的电影的反应.
结论:
- 瞳孔测量有效地测量了瞳孔调节中的特异性,即使在患有自闭症和智力障碍的幼儿中也是如此.
- 自闭症儿童表现出不那么稳定的,更奇特的瞳孔调节,表明神经活动更可变.
- 瞳孔测量是了解自闭症谱系障碍中神经调节差异的宝贵工具.
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