多种维生素对神经和生长障碍的影响:一个横截面研究
Jiaxiao Zhu1, Penghong Xu2, Wu Yan3
1Department of Pediatrics, Nanjing Medical University, Nanjing, China.
Frontiers in nutrition
|October 10, 2024
概括
过度摄入维生素可能会给健康带来风险. 这项研究发现,多种维生素可能与神经和生长障碍有关,其影响因维生素类型和障碍而异.
科学领域:
- 营养科学 营养科学
- 儿科健康 儿科健康
- 神经学 神经学
背景情况:
- 虽然维生素缺乏是已知的健康风险,过量摄入维生素也可能是有害的.
- 关于多种维生素消费对儿童神经和生长障碍的具体影响的数据有限.
- 了解这些关联对于公共卫生和临床实践至关重要.
研究的目的:
- 研究复合维生素摄入量与发展神经和生长障碍的风险之间的关系.
- 在复合维生素中识别可能影响这些疾病的特定维生素.
主要方法:
- 一项涉及16921名受试者的横截面研究 (神经/生长障碍病例和健康对照).
- 统计分析包括T测试,威尔科克森等级总和测试,奇方位测试,后勤回归和加权量子总和 (WQS) 回归.
- 分析的维生素包括血清25-基维生素D [25(OH) D],B2,B9,A,B1,B12,C,以及多维生素配方中的其他维生素.
主要成果:
- 经调整后勤回归显示,特定维生素与神经系统疾病风险之间存在关联 (例如,25~OH) D,B2,B9的风险降低;A,B1,B12的风险增加).
- 维生素A和维生素B2与增长障碍的风险增加有关.
- WQS回归表明9种复合维生素与神经疾病风险之间存在积极关联,维生素D和维生素C的权重最高. 与生长障碍的关联通常是相反的,但不显著,尽管肥胖和营养不良显示出积极的联系.
结论:
- 多种维生素可能与神经和生长障碍有关.
- 这些关联的方向和意义取决于特定的维生素和疾病类型.
- 需要进一步的研究来阐明多种维生素摄入量与儿科健康结果之间的复杂相互作用.
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