身体质量指数与炎症因素相结合,可以更好地预测静脉
Si Yan Miao1, Wen Rui Wu1, Liang Feng1
1Department of Urology, The First Affiliated Hospital of Nanchang University, Nanchang, CHN.
Cureus
|October 10, 2024
概括
在不孕症诊断过程中,常常会发现静脉 (VC). 系统性免疫炎症指数 (SII) 和中性粒细胞-淋巴细胞比率 (NLR) 是危险因素,而较高的体重指数 (BMI) 是保护性的. 将BMI与SII和NLR结合起来可以改善VC预测.
科学领域:
- 泌尿器科 泌尿器科 泌尿器科 泌尿器科
- 安德罗学与人类学
- 炎症研究 炎症研究
背景情况:
- 静脉 (VC) 是男性不孕症的常见原因,通常无症状,诊断迟到.
- 早期发现VC对于及时的临床干预至关重要.
- 了解VC的风险和保护因素对于改进诊断策略至关重要.
研究的目的:
- 为了确定瘤 (VC) 的独立风险和保护因素.
- 评估这些因素的诊断价值,单独或组合,用于预测VC.
- 探索身体质量指数 (BMI) 与炎症标志物相结合的预测准确度.
主要方法:
- 423名患者的临床数据的回顾性分析 (2021年1月至2024年2月).
- 倾向性得分匹配 (PSM) 创建两个可比的组 (VC和非VC).
- 多变量二进制后勤回归和接收器操作特征 (ROC) 曲线分析.
主要成果:
- 系统性免疫炎症指数 (SII) 和中性粒细胞-淋巴细胞比率 (NLR) 是VC的独立风险因素 (p<0.05).
- 较高的身体质量指数 (BMI) 是对VC的独立保护因素 (p<0.05).
- 与炎症因素 (SII,NLR) 结合的BMI显著提高了VC预测准确度 (87.5%),而不是单个因素.
结论:
- SII和NLR是发生瘤的重要危险因素.
- 体重指数 (BMI) 起到保护性因素的作用,可以防止水.
- 将BMI与SII和NLR结合起来,可以提供更准确的静脉检测预测模型.
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