1991年至2022年希腊多胎和早产率之间的强烈相关性
Nikolaos Vlachadis1, Dionysios N Vrachnis2, Nikolaos Loukas3
1Department of Obstetrics and Gynecology, General Hospital of Messinia, Kalamata, GRC.
Cureus
|October 10, 2024
概括
该研究发现,从1991年到2022年,希腊多胎儿和早产儿的增加之间存在着强烈的联系. 多胎妊娠显著增加了早产率的增加,突出了一个关键的公共卫生问题.
科学领域:
- 生殖健康 生殖健康
- 周围生理学 周围生理学
- 公共卫生统计 公共卫生统计
背景情况:
- 希腊的早产率 (PBR) 在1991年至2022年间有所上升.
- 多胎儿是早产的已知危险因素之一.
研究的目的:
- 调查1991年至2022年希腊早产率 (PBR) 的上升与多胎儿发病率之间的相关性.
- 量化多胎妊娠对早产趋势的影响.
主要方法:
- 利用希腊统计局 (1991-2022) 的官方活生儿出生数据.
- 计算PBR (<37周) 和每100个活产多胎率 (MBR).
- 使用斯皮尔曼的等级相关性和线性回归模型来评估相关性.
主要成果:
- 在PBR和MBR之间观察到非常强的正相关性 (斯皮尔曼的rho=0.950,p<0.001).
- 线性回归表明MBR解释了PBR上升的83.8% (R-平方 = 0.838).
- 这种相关性在中度和晚期早产中最强,在1991-2011年期间特别高.
结论:
- 在希腊,多胎儿出生率与早产率之间存在显著的积极关联.
- 多胎妊娠是观察到的早产增加的主要驱动因素.
- 这些发现强调了针对多胎妊娠的有针对性的干预措施的必要性,以减少早产.
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