膝关节关节炎的严重程度,膝关节疼痛和抑郁症对身体功能的影响:一个横截面研究
Tatsuru Sonobe1, Koji Otani1, Miho Sekiguchi1
1Department of Orthopaedic Surgery, Fukushima Medical University School of Medicine, Fukushima, 960-1295, Japan.
Clinical interventions in aging
|October 10, 2024
概括
严重的膝关节疼痛和抑郁症在膝关节骨关节炎 (KOA) 患者的身体功能上显著影响. 放射性严重程度不那么重要,强调需要解决疼痛和心理健康问题,以获得更好的身体功能结果.
科学领域:
- 老年学是一门学科.
- 公共卫生 公共卫生
- 整形外科 整形外科 整形外科
背景情况:
- 全球预期寿命正在增加,导致与年龄相关的健康问题增加.
- 身体功能下降是一个主要的公共卫生问题,膝关节骨关节炎 (KOA) 是主要的贡献者.
- 抑郁症与身体功能下降有关,并在KOA患者中加剧膝盖疼痛,但它们的综合效果仍然不清楚.
研究的目的:
- 为了研究身体功能,放射性膝关节骨关节炎 (KOA) 严重程度,膝关节疼痛和抑郁症之间的关联.
- 澄清这些因素对老龄化人口身体功能的独立和综合影响.
主要方法:
- 对来自2009年"爱苏队列研究 (LOHAS) 中的机车综合征和健康结果" (Locomotive Syndrome and Health Outcome in Aizu Cohort Study) 1106名参与者的基线数据进行横截分析.
- 通过多变量分析,评估了定时启动和启动 (TUG) 测试分数 (表明身体功能) 与放射性KOA,膝盖疼痛和抑郁症之间的关联.
主要成果:
- 严重的膝盖疼痛与身体功能下降显著相关 (OR 2.13,95% CI:1.32-4.89).
- 抑郁症也与身体功能下降显著相关 (OR2.64,95% CI:1.61-4.33).
- 只有严重的放射性KOA (Kellgren-Lawrence 4级) 显示出与身体功能下降的显著关联 (OR 6.58,95% CI: 1.75-24.68).
结论:
- 严重的膝盖疼痛和抑郁症是导致KOA患者身体功能减弱的关键因素.
- 仅仅放射性KOA的严重程度是身体功能的不太可靠指标,除了最严重的病例 (KL级4).
- 在KOA中对身体功能的临床评估应将患者报告的膝盖疼痛和心理因素与放射性发现相结合.
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