在患有性结肠炎的妇女和健康人群中比较盆地功能障碍
Maryam Soheilipour1, Babak Tamizi Far1, Razieh Fadaei1
1Gastroenterology and Hepatology Research Center, Isfahan University of Medical Sciences, Isfahan, Iran.
Middle East journal of digestive diseases
|October 10, 2024
概括
患有性结肠炎 (UC) 的女性患有盆地功能障碍 (PFD) 的患病率更高. 老龄化,BMI和更年期等因素也会导致UC患者的PFD.
科学领域:
- 胃肠病学 胃肠病学
- 泌尿和妇科 泌尿和妇科
- 妇女健康 妇女健康
背景情况:
- 炎症性肠病 (IBD),特别是性结肠炎 (UC),与功能性胃肠道疾病有关.
- 这些胃肠道问题可能会增加患有骨盆底功能障碍 (PFD) 的风险.
- 与健康对照组相比,患有UC的女性中PFD的患病率和特异性影响需要进一步调查.
研究的目的:
- 评估女性性结肠炎 (UC) 和骨盆底功能障碍 (PFD) 之间的关联.
- 为了比较患有UC的女性中的PFD患病率,与没有IBD的对照组进行比较.
- 为了确定最受UC影响的PFD的特定子域.
主要方法:
- 一项涉及150名被诊断患有UC的妇女和150名没有IBD的健康妇女的比较研究.
- 骨盆地功能使用骨盆地危害清单 (PFDI-20) 进行评估.
- 进行了统计分析,以确定UC和其他因素对PFD得分的重要性.
主要成果:
- 与对照组相比,患有UC的女性的总体PFD得分明显高于对照组 (Beta=3.04;P<0.001).
- 特定的子尺度,包括盆腔器官缩应激清单 (POPDI) 和色直肠门应激清单 (CRADI),显示UC患者的显著增加 (Beta=6.61,P<0.001和Beta=9.37,P<0.001分别).
- 老龄化,体重指数 (BMI) 增加和更年期被确定为增加PFD得分 (POPDI,UDI,PFDI) 的重要因素.
结论:
- 性结肠炎与女性的骨盆底功能障碍发病率较高显著相关.
- 在UC患者的骨盆底功能障碍在与骨盆器官脱落和色直肠关痛相关的领域特别明显.
- 除了UC外,人口统计和健康因素,如年龄,BMI和更年期状态在PFD的发展和严重程度方面发挥着至关重要的作用.
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