瘤微环境控制了头支状细胞癌免疫疗法的预后格局:以计算模型为指导的分析

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Updated: Jun 14, 2025

Intramucosal Inoculation of Squamous Cell Carcinoma Cells in Mice for Tumor Immune Profiling and Treatment Response Assessment
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Intramucosal Inoculation of Squamous Cell Carcinoma Cells in Mice for Tumor Immune Profiling and Treatment Response Assessment

Published on: April 22, 2019

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Priyan Bhattacharya1, Alban Linnenbach2, Andrew P South3

  • 1Department of Pathology and Genomic Medicine, Thomas Jefferson University, Philadelphia, PA19107, USA.

bioRxiv : the preprint server for biology
|October 10, 2024
PubMed
概括

这项研究模拟了头部和部状细胞癌瘤微环境 (TME),以了解免疫检查点抑制剂 (ICI) 耐药性. 独特的TME亚型决定了ICI反应,揭示了改善结果的特定治疗目标.

关键词:
抗癌能力 抗癌能力计算建模计算建模头部和部状细胞癌瘤免疫治疗是一种免疫疗法.系统生物学 系统生物学瘤微环境是一个微环境.

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