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Updated: Jun 11, 2025

Engineering Artificial Factors to Specifically Manipulate Alternative Splicing in Human Cells
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在人类乳腺癌中可移植元素的替代拼接

Alex Nesta1,2, Diogo F T Veiga3, Jacques Banchereau1,4

  • 1The Jackson Laboratory for Genomic Medicine, Farmington, CT 06032 USA.

bioRxiv : the preprint server for biology
|October 10, 2024
PubMed
概括

可移植元素 (TE) 通过创造新的拼接事件和改变基因表达,显著影响乳腺癌转录组. 长读测序揭示了TE驱动的异型,这些异型可能作为新的治疗点或生物标志物.

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