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Updated: Jun 11, 2025

A Guide to Production, Crystallization, and Structure Determination of Human IKK1/α
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A Guide to Production, Crystallization, and Structure Determination of Human IKK1/α

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延长IKK激活的时间变化的刺激促进了核重塑和NF-κB动态的机械切换

Steven W Smeal1, Chaitanya S Mokashi1,2, A Hyun Kim1

  • 1Department of Computational and Systems Biology, School of Medicine, University of Pittsburgh, Pittsburgh, PA 15213, USA.

bioRxiv : the preprint server for biology
|October 10, 2024
PubMed
概括

细胞信号的动态,如蛋白质的变化,指导反应. 这项研究揭示了重复的细胞因子信号如何延长IκB激酶 (IKK) 组合,增强核因子 κB (NF-κB) 保留并影响细胞行为.

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