David M Renner1,2, Nicholas A Parenti1,2, Susan R Weiss1,2

  • 1Departments of Microbiology, Perelman School of Medicine, University of Pennsylvania, Philadelphia, PA, USA 19104-6076.

概括

像MERS-CoV和HCoV-OC43这样的人类β冠病毒依赖于去酸化eIF2α进行复制,与耐受高水平的SARS-CoV-2不同. 病毒策略的这种差异是开发向治疗的关键.

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Stress Response System01:21

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