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膀Ewing肉瘤的单细胞RNA测序和空间转录组学

Weipu Mao1, Kangjie Xu2, Keyi Wang3

  • 1Department of Urology, Affiliated Zhongda Hospital of Southeast University, Nanjing 210009, China.

iScience
|October 10, 2024
PubMed
概括

研究人员在膀中发现了新型细胞类型和信号通路 尤文肉瘤/原始神经外皮瘤 (ES/PNET). 巨细胞通过TNFSF12-TNFRSF12A信号激活上皮细胞,这表明Enavatuzumab是潜在的治疗方法.

关键词:
癌症 癌症 癌症 癌症 癌症分子生物学分子生物学翻译学 翻译学 翻译学 翻译学

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相关概念视频

RNA-seq03:21

RNA-seq

RNA sequencing, or RNA-Seq, is a high-throughput sequencing technology used to study the transcriptome of a cell. Transcriptomics helps to interpret the functional elements of a genome and identify the molecular constituents of an organism. Additionally, it also helps in understanding the development of an organism and the occurrence of diseases. 
Before the discovery of RNA-seq, microarray-based methods and Sanger sequencing were used for transcriptome analysis. However, while microarray-based...