入院时的肝功能异常预测了消化系统中的长期COVID综合征
Huibin Wu1, Yunjie Zhang2, Wenqing Tang1
1Department of Gastroenterology and Hepatology, Shanghai Institute of Liver Diseases, Zhongshan Hospital, Fudan University, Shanghai, 200032, China.
Heliyon
|October 10, 2024
概括
住院时出现肝功能异常的COVID-19患者患上消化系统长期COVID综合征的风险更高. 这一发现突显了长期COVID发展的一个关键因素.
科学领域:
- 胃肠病学 胃肠病学
- 传染性疾病 传染性疾病
- 流行病学 流行病学
背景情况:
- 消化系统功能障碍是长期COVID综合征的常见表现.
- 识别导致长期COVID的胃肠道影响的因素对于患者护理至关重要.
研究的目的:
- 调查影响长期COVID综合征影响消化系统的发生率的因素.
- 为了确定入院肝功能和消化长期COVID之间的关联.
主要方法:
- 一项队列研究涉及494名患有SARS-CoV-2感染的患者,涉及三个医院中心.
- 修改Poisson回归分析用于计算相对风险 (RR).
- 患者在消化系统中被监测到COVID-19后急性后果的发展.
主要成果:
- 144名患者 (29.1%) 在入院时有肝功能异常.
- 消化性长期COVID发生在20.8%的入院肝脏异常患者中,而没有5.7%的患者中.
- 入院肝功能异常与3.55倍的风险增加有关 (RR=3.550,95% CI:2.099-6.006).
结论:
- 住院时肝功能异常是发展消化系统长期COVID的重要风险因素.
- 早期识别肝功能问题可能有助于预测和管理长期COVID胃肠道症状.
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