在COVID-19大流行期间使用多重呼吸板测试的变化
Jonathan D Baghdadi1,2, Chih Chun Tung3, J Kristie Johnson1,4
1Department of Epidemiology and Public Health, University of Maryland School of Medicine, Baltimore, MD, USA.
Infection control and hospital epidemiology
|October 10, 2024
概括
流行后的呼吸道病毒检测转向较小的多重核酸放大面板. 这种变化可能是由成本,资源可用性和专注于特定病原体的因素驱动的.
科学领域:
- 临床微生物学 临床微生物学
- 流行病学 流行病学
- 医疗保健服务研究 医疗服务研究
背景情况:
- COVID-19 流行病显著改变了社区获得的呼吸道病毒的格局.
- 了解呼吸道病毒检测模式对于优化后流行病时代的临床效用至关重要.
研究的目的:
- 分析呼吸道病毒面板测试利用的趋势.
- 为了比较大流行前,大流行初期和大流行后期的测试模式.
- 为了识别急性护理环境中使用的呼吸板类型的变化.
主要方法:
- 使用PINC-AI行政豁免数据进行回顾性观察研究.
- 在三个时期的多重核酸放大呼吸系统面板使用 (小,中,大) 的比较:大流行前 (2019年11月-2020年2月),早期大流行 (2020年3月-2020年10月) 和晚期大流行 (2020年11月-2020年4月2021年).
- 使用ANOVA进行统计分析,以确定测试利用率的显著差异.
主要成果:
- 整体呼吸系统面板利用率在流行病早期下降,但在流行病后期恢复到流行病前的水平.
- 观察到测试组合的显著转变,在流行病晚期与流行病前相比,小面板的使用增加,大面板的使用减少.
- 统计分析证实,在研究期间,总体测试,大面板使用和小面板使用之间存在显著差异 (P < 0.0001).
结论:
- 流行后的时代的特点是呼吸系统面板测试从大型,全面的面板转向更小,更有针对性的面板.
- 这种转变可能会受到诸如资源限制,成本效益以及临床关注确定关键病原性病毒等因素的影响.
- 这些发现突出了呼吸道病毒诊断的不断发展的战略,以提高临床效用和效率.
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