基于TianTan vaccinia病毒的EBV疫苗,针对潜伏和溶性抗原,在人性化的小鼠中引起了对致命的EBV挑战的强有力的免疫力

Xinyu Zhang1, Yanhong Chen1, Shuhui Wang2

  • 1State Key Laboratory of Oncology in South China, Collaborative Innovation Center for Cancer Medicine, Guangdong Key Laboratory of Nasopharyngeal Carcinoma Diagnosis and Therapy, Guangdong Provincial Clinical Research Center for Cancer, Sun Yat-sen University Cancer Center, Guangzhou, People's Republic of China.

PubMed
概括

开发爱斯坦-巴尔病毒 (EBV) 疫苗需要针对多个病毒阶段. 表达关键EBV蛋白质的多抗原疫苗通过激活T细胞反应,有望预防EBV诱导的淋巴瘤.