健康儿童右心房的大小和功能 通过三维心声谱
Brendan Haughian1,2, Pei-Ni Jone3,4,5, Lisa Le3
1Stollery Children's Hospital, Edmonton, Alberta, Canada.
Echocardiography (Mount Kisco, N.Y.)
|October 10, 2024
概括
本研究确定了使用3D心声回声学对儿童右心房体积和功能的正常参考值. 确定了最佳的索引方法,比传统的身体表面积计算提高了准确性.
科学领域:
- 儿童心脏病学 儿童心脏病学
- 心声回声扫描 (Echocardiography) 是一种心声回声扫描.
- 心脏成像 - - 心脏成像
背景情况:
- 右心房体积和功能是心脏病的关键预后指标.
- 三维心声回声 (3DE) 为评估右心房 (RA) 参数提供了更高的准确性.
- 缺乏使用3DE的儿科RA体积和功能的确定的正常参考值.
研究的目的:
- 为了确定健康儿童的3DE衍生右心房体积 (RAV) 和功能的正常参考值.
- 为了比较不同的回归方法 (身体表面积,身高,体重,性别) 来索引这些儿科RA测量.
- 将3DE衍生值与从二维心声回声 (2DE) 中获得的值进行比较.
主要方法:
- 从两个国际中心的187名健康儿童的3DE数据集进行了回顾性分析.
- 使用不依赖供应商的软件测量3DE体积,并通过面积-长度方法测量2DE终端透气体积 (EDV).
- 探索回归曲线适合身高,体重,BSA和性别,以优化同性恋和相关性.
主要成果:
- 将3DE RAV索引到单独的BSA导致了异种性.
- 使用结合身高,体重和性别的模型实现了最佳的同性遗传回归.
- 总的RA排空分数没有显示年龄或性别变化,而主动和被动排空最好用脊柱曲线来描述.
- 在3DE和2DE衍生EDV之间观察到很强的一致性 (r2 = 0.83).
结论:
- 这项研究提供了由3DE评估的儿科RA大小和功能的基本参考值.
- 已经确定了一种超越BSA单独的,用于索引儿科RA测量的优质方法.
- 这些发现有助于在儿科心脏病中更准确的预后评估.
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