ALKBH5-介导的m6XBP1的修改促进NSCLC通过IL-6-JAK-STAT3路径的进展

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Hengxing Liang1,2, Chunmin Zhang3, Minxin Hu4

  • 1Department of Thoracic Surgery, Guilin Hospital of the Second Xiangya Hospital CSU, Guilin, China.

Molecular carcinogenesis
|October 10, 2024
PubMed
概括

在非小细胞肺癌 (NSCLC) 中,N6-甲基氨酸 (m6A) RNA修饰调节X盒结合蛋白1 (XBP1). ALKBH5和IGF2BP3通过稳定XBP1mRNA,激活IL-6-JAK-STAT3通路来促进NSCLC的进展.

关键词:
在 ALKBH5H5 中在 IGF2BP3BP3 中.N6 - 甲基氨酸 (m6A) 的使用.在XBP1中使用.非小细胞肺癌 (NSCLC) 是一种非小细胞肺癌.

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