Drp1通过驱动线粒体裂变来促进宏M1极化和自身免疫性心肌炎的炎症反应

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Lin Lin1, Jin Wei2, Jiahong Xue2

  • 1Department of Cardiovascular Medicine, Cardiovascular Hospital of the Second Affiliated Hospital of Xi'an Jiaotong University, Daminggong Campus, No. 5 Jianqiang Road, Xi'an, 710016, Weiyang District, China. lin_linvas@126.com.

Journal of cardiovascular translational research
|October 10, 2024
PubMed
概括

动氨酸相关蛋白1 (Drp1) 通过促进巨细胞中的线粒体裂变来驱动自身免疫性心肌炎的炎症. 抑制Drp1可降低心脏炎症,并可能为这种疾病提供治疗点.

关键词:
自身免疫性心肌光学DRP1 是一个DRP1EAM鼠标模型的模型.在M1极化中,M1极化线粒体裂变的线粒体裂变

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