甲状腺癌发生率在2020年至2021年期间COVID-19变种波浪
Rebecca Bell1,2, Daniel M Weinberger3, Manasa Venkatesh4
1Section of Otolaryngology-Head & Neck Surgery, Dartmouth-Hitchcock Medical Center, Lebanon, New Hampshire.
JAMA otolaryngology-- head & neck surgery
|October 10, 2024
概括
由于COVID-19的流行,到2021年底,估计有10,200例未被诊断的甲状腺癌病例. 这种诊断缺陷,特别是对于乳头甲状腺癌,可能会增加未来患者的发病率和死亡率.
科学领域:
- 在瘤学瘤学.
- 流行病学 流行病学
- 公共卫生 公共卫生
背景情况:
- 2020年至2021年期间COVID-19变种对甲状腺癌诊断率的影响仍然未被描述.
- 了解这些诊断趋势对于评估潜在的长期健康影响至关重要.
研究的目的:
- 在COVID-19大流行 (2020-2021) 的前两年,根据组织学类型估计未诊断的甲状腺癌的数量.
- 为了比较观察到的与预期的癌症发病率.
- 为了评估在此期间与前几年相比,诊断时癌症大小的变化.
主要方法:
- 从2016年到2021年对甲状腺癌诊断的纵向分析.
- 利用了美国监测,流行病学和最终结果 (SEER-22) 计划的数据.
- 计算年龄调整的发病率,发病率的变化,估计未诊断的病例和平均癌症大小.
主要成果:
- 从2020年3月到2021年12月,甲状腺癌发病率在所有主要组织学类型中显著下降,包括乳头癌,卵泡癌,髓癌和形癌.
- 在此期间,估计有10200例甲状腺癌未被诊断出来,主要是较小的乳腺癌.
- 诊断时的平均癌症大小在研究期间没有显著变化.
结论:
- 由于COVID-19的流行,到2021年底,甲状腺癌的诊断出现了严重的缺陷,影响了大多数组织学类型.
- 这种诊断差距,特别是对于较小的乳头癌,可能会导致未来出现晚期疾病的患者数量增加.
- 由于诊断延迟或错过,预计会导致人口发病率和死亡率的潜在增加.
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