通过重新分配未使用的口服抗癌药物来减少药物浪费的环境结果
Elisabeth M Smale1, Anne B Ottenbros2, Bart J F van den Bemt1,3
1Department of Pharmacy, Radboud University Medical Center, Nijmegen, the Netherlands.
JAMA network open
|October 10, 2024
概括
重新分配未使用的口服抗癌药物提供了一个可持续的解决方案,以尽量减少癌症治疗中的浪费. 优化流程,特别是对于温度敏感药物,为人类健康和生态系统带来了环境效益.
科学领域:
- 环境科学 环境科学
- 在瘤学瘤学.
- 可持续的药房实践可持续的药房实践
背景情况:
- 药物对环境的影响有很大影响,大量的废物来自未使用的药物.
- 口服抗癌药物,往往未被患者使用,是制药浪费的重要来源.
- 减少废物干预对于减少癌症治疗对环境的影响至关重要.
研究的目的:
- 评估重新分配质量保证的口服抗癌药物的环境结果.
- 探索优化药物再分配过程的环境可持续性的方法.
主要方法:
- 一项前性多中心质量改进研究,涉及荷兰4家医院的1071名癌症患者.
- 从摇篮到坟墓的生命周期评估口服抗癌药物在12个月的随访期内重新分配.
- 评估环境结果,包括人类健康 (残疾调整寿命),生态系统损害 (物种×年) 和气候变化 (千克CO2eq).
主要成果:
- 最初的重新分配造成了环境负担,主要是由于时间温度指标.
- 对温度敏感药物 (≤25°C) 选择性使用质量保证材料被证明是对环境有益的.
- 优化的再分配产生了每年每名患者1.9公斤二氧化碳等值的气候效益,以及对人类健康和生态系统的积极影响.
结论:
- 重新分配未使用的口服抗癌药物是减少浪费和提高癌症护理环境可持续性的可行策略.
- 过程优化,特别是对质量保证材料的合理使用,是实现环境效益的关键.
- 这种方法可以有助于降低成本和环境结果,支持一个更可持续的医疗保健系统.
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