揭示联系:双甲和维生素D在健康哺乳母亲的母乳中的动态
Esra Cinkilli Aktağ1,2, Sıddika Songül Yalçin1, Anıl Yіrün3,4
1Department of Social Pediatrics, Institute of Child Health, Hacettepe University, Ankara, Türkiye.
International journal of environmental health research
|October 10, 2024
概括
这项研究没有发现健康母亲母乳中双甲 (BPA) 含量和25 (OH) 维生素D含量之间的联系. 需要进一步的研究才能充分理解这些因素.
科学领域:
- 环境健康 环境健康
- 人类营养人类营养
- 内分泌学 在内分泌学.
背景情况:
- 双A (BPA) 是一种环境污染物,已知对健康有不良影响.
- 维生素D对婴儿健康至关重要,母乳是主要来源.
- 了解环境暴露和母乳中的营养水平之间的潜在相互作用对于母亲和儿童的健康至关重要.
研究的目的:
- 调查人类母乳中双甲 (BPA) 含量和25 (OH) 维生素D度之间的关联.
- 探索哺乳期母亲队列中的潜在相关性.
主要方法:
- 数据收集包括BPA暴露和维生素D来源信息.
- 用竞争性酶相关免疫吸收试验 (ELISA) 分析了母乳样本的25(OH) 维生素D.
- 使用光探测器的高性能液体染色学 (HPLC) 来量化双甲 (BPA) 含量.
- 统计分析涉及单变量和多变量逻辑回归模型.
主要成果:
- 共有70名哺乳期母亲参加了这项研究.
- 母乳中维生素D水平的中位数为12.6 ng/mL.
- 在92.9%的样本中存在可检测到的Bisphenol A (BPA),平均度为2.56 ng/mL.
- 没有发现母乳中双甲 (BPA) 含量与25OH) 维生素D度之间有统计学意义的关联.
结论:
- 该研究没有发现健康哺乳母亲母乳中的双甲 (BPA) 和25 (OH) 维生素D之间的相关性.
- 这些发现表明,在这些条件下,BPA暴露似乎不会直接影响母乳中的维生素D水平.
- 需要进行进一步的研究,以探索不同人群或不同暴露场景中的潜在间接影响或关联.
更多相关视频
04:16Individualized Reconstitution of Human Milk Microbiota: A Feasible Approach in Real-World Settings
Published on: February 7, 2025
404
06:47Isolation of Mesenchymal Stem Cells from Human Alveolar Periosteum and Effects of Vitamin D on Osteogenic Activity of Periosteum-derived Cells
Published on: May 4, 2018
9.3K
相关概念视频
01:25Role of Vitamins in Maintaining Bone Health
3.2K
The growth and maintenance of bone are regulated by a combination of nutritional factors, including vitamins, such as vitamin A, B12, C, D, and K.
Vitamin A
Vitamin A is involved in the process of bone remodeling. Retinoic acid, the active metabolite of Vitamin A, has nuclear receptors in osteoblasts and osteoclasts, which are involved in bone remodeling.
Vitamin B12
Vitamin B12 acts as a cofactor during the formation of osteoblast-related proteins, such as osteocalcin. Vitamin B12 plays a role...
Vitamin A
Vitamin A is involved in the process of bone remodeling. Retinoic acid, the active metabolite of Vitamin A, has nuclear receptors in osteoblasts and osteoclasts, which are involved in bone remodeling.
Vitamin B12
Vitamin B12 acts as a cofactor during the formation of osteoblast-related proteins, such as osteocalcin. Vitamin B12 plays a role...
3.2K
01:23Role of Skin in Vitamin D Synthesis
5.1K
The skin plays a crucial role in the synthesis of vitamin D, a vital nutrient for various physiological processes in the body. Vitamin D is unique because it can be synthesized in the skin through a series of chemical reactions triggered by exposure to ultraviolet B (UVB) radiation from sunlight.
The solar UV B rays (290-315 nm) are absorbed by the skin, and 7-dehydrocholesterol (provitamin D3) photolyzes it to previtamin D3, which undergoes a rapid transformation to vitamin...
The solar UV B rays (290-315 nm) are absorbed by the skin, and 7-dehydrocholesterol (provitamin D3) photolyzes it to previtamin D3, which undergoes a rapid transformation to vitamin...
5.1K
01:17Hormones and Bone Tissue
2.6K
The endocrine system produces and secretes hormones, which interact with the skeletal system. These hormones control bone growth, maintain bone once it is formed, and remodel it.
Hormones That Influence Osteoblasts and/or Maintain the Matrix
Several hormones are necessary for controlling bone growth and maintaining the bone matrix. The pituitary gland secretes growth hormone (GH), which, as its name implies, controls bone growth. This happens in several ways: first, it triggers chondrocyte...
Hormones That Influence Osteoblasts and/or Maintain the Matrix
Several hormones are necessary for controlling bone growth and maintaining the bone matrix. The pituitary gland secretes growth hormone (GH), which, as its name implies, controls bone growth. This happens in several ways: first, it triggers chondrocyte...
2.6K
01:29Factors Affecting Protein-Drug Binding: Patient-Related Factors
45
Protein-drug binding, a pivotal aspect of pharmacokinetics, is subject to considerable variability influenced by an array of patient-related factors. The intricate interplay of age, individual differences, and pathological conditions significantly impact the binding dynamics and subsequent pharmacological effects.
Age stands as a key determinant in protein-drug binding. Neonates, characterized by low albumin content, experience heightened concentrations of unbound drugs such as phenytoin and...
Age stands as a key determinant in protein-drug binding. Neonates, characterized by low albumin content, experience heightened concentrations of unbound drugs such as phenytoin and...
45
01:19Factors Affecting Drug Biotransformation: Biological
123
Biological factors significantly impact drug metabolism, influencing drug clearance, efficacy, and potential toxicity.
Species differences: Variations in enzyme systems across species can cause disparities in drug metabolism. For instance, humans may metabolize certain drugs faster than rodents, altering therapeutic effects.
Strain differences: Genetic variations within a species can result in differing enzyme activity, impacting drug response and toxicity. For example, some mouse strains may...
Species differences: Variations in enzyme systems across species can cause disparities in drug metabolism. For instance, humans may metabolize certain drugs faster than rodents, altering therapeutic effects.
Strain differences: Genetic variations within a species can result in differing enzyme activity, impacting drug response and toxicity. For example, some mouse strains may...
123
01:30Vitamins
576
Vitamins, derived from the Latin word for life, are essential organic substances required in small quantities for optimal growth and overall well-being. Unlike other organic nutrients, vitamins don't act as sources of energy or building materials but rather facilitate these nutrients' utilization by the body. Vitamins are predominantly coenzymes, assisting enzymes in specific chemical actions, like the oxidation of glucose for energy involving B vitamins. Most vitamins are not produced...
576