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Updated: May 6, 2026

Sequencing of mRNA from Whole Blood using Nanopore Sequencing
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基准测试揭示了深度学习变体调用者的优越性在细菌纳米孔序列数据上

Michael B Hall1, Ryan R Wick1,2, Louise M Judd1,2

  • 1Department of Microbiology and Immunology, The University of Melbourne, at the Peter Doherty Institute for Infection and Immunity, Melbourne, Australia.

eLife
|October 10, 2024
PubMed
概括

牛津纳米孔技术 (ONT) 测序与深度学习变体调用器,如Clair3和DeepVariant提供优越的细菌基因组学精度. 这种方法超越了Illumina测序,即使在较低的读取深度,使其成为资源有限的设置的理想选择.

关键词:
在C. jejuniuni的研究中.美国大肠杆菌 (E. coli).在K. pneumoniae的肺炎中.L.单细胞原体.在M.结核病.黄金色的S. 黄金色的在S. enterica中发现的.在S. pyogenes的基础上.细菌 细菌 细菌是一种细菌.一个基准的基准指标.生物信息学是一种生物信息学.计算生物学是计算生物学.深度学习是一种深度学习.传染病是一种传染性疾病.微生物学的微生物.这是一个纳米孔.系统生物学 系统生物学变量调用变量调用

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