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对抗SARS-CoV-2变种的索特罗维马布中和能力的比较:快速计算方法的开发

Dana Ashoor1, Maryam Marzouq1, M-Dahmani Fathallah1

  • 1Department of Life Sciences, Health Biotechnology Program - King Fahad Chair for Health Biotechnology, College of Graduate Studies, Arabian Gulf University, Manama, Bahrain.

JMIR bioinformatics and biotechnology
|October 10, 2024
PubMed
概括

一种新的计算方法快速评估针对SARS-CoV-2变体的单克隆抗体疗效. 它发现对Omicron变种的结合性下降,突出了像G339H/D这样的突变,使免疫逃避成为可能.

关键词:
这就是Omicron.在S309中,S309是S309中的一个.这就是SARS-CoV-2病毒.这就是Sotrovimab.氨基酸氨基酸是一种氨基酸.抗SARS-CoV-2病毒的方法计算方法是一种计算方法.在的中.一个单克隆的单克隆.突变是一种突变.中和抗体的抗体中和.蛋白质蛋白质是蛋白质蛋白质的组成部分.亚变种的子变种变种变种的变种

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A single nucleotide polymorphism or SNP is a single nucleotide variation at a specific genomic position in a large population. It is the most prevalent type of sequence variation found in the human genome. Point mutations that occur in more than 1% of the population qualify as SNPs. These are present once every 1000 nucleotides on an average in the human genome. Replacement of a purine with another purine (A/G) or a pyrimidine with another pyrimidine (C/T) is known as a transition. In contrast,...
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