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Updated: Jun 10, 2025

Identification of Transcription Factor Regulators using Medium-Throughput Screening of Arrayed Libraries and a Dual-Luciferase-Based Reporter
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一个MYC-STAMBPL1-TOE1正反循环调解了肝细胞癌中的EGFR稳定性

Hongli Zhang1, Zixuan Wang1, Jian Zhang2

  • 1State Key Laboratory of Chemical Resource Engineering, College of Life Science and Technology, Beijing University of Chemical Technology, Beijing, P.R. China.

Cell reports
|October 10, 2024
PubMed
概括

通过稳定EGFR蛋白和mRNA,STAMBPL1二维基因酶对肝癌产生影响. 抑制STAMBPL1或TOE1增强了伦瓦替尼的作用.

关键词:
CP: 癌症 癌症 癌症欧洲农业基金会 (EGFR) 是一个基金.肝细胞癌是肝细胞癌.我的世界 MYC通过RNA拼接进行RNA拼接.在STAMBPL1中使用.这是一个 TOE1 TOE1 TOE1必须进行脱离分离.

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