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Updated: Jun 10, 2025

Real-Time Analysis of Bioenergetics in Primary Human Retinal Pigment Epithelial Cells Using High-Resolution Respirometry
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缺少Rheb1会引起线粒体功能障碍,并通过促进Atp5f1c乙化来加速皮细胞衰老

Qingmiao Lu1, Xiao Hu2, Qing Hou3

  • 1Department of Endocrinology, 2(nd) Affiliated Hospital, Nanjing Medical University, 121 Jiangjiayuan, Nanjing, Jiangsu, China.

Cellular signalling
|October 10, 2024
PubMed
概括

缺少Rheb1会通过损害线粒体功能来加速皮质细胞衰老和病,这种功能独立于mTORC1的信号传递. 这一发现为糖尿病病 (DKD) 提供了新的治疗点.

关键词:
糖尿病脏疾病 糖尿病脏疾病线粒体中的线粒体.足细胞衰老 足细胞衰老这就是Rheb1的意思.

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