预药物治疗,以减少侵入性表面活性剂的使用:叙述性综述
Claire A Murphy1, Kevin Cw Goss2, Rebeccah Slater3
1Neonatal Medicine, Chelsea and Westminster Healthcare NHS Trust, London, UK drclaireamurphy@gmail.com.
Archives of disease in childhood. Fetal and neonatal edition
|October 10, 2024
概括
对于早产婴儿,少侵入性表面活性剂 (LISA) 的使用需要有效的疼痛管理. 本综述检查了当前的知识和证据差距关于前期治疗策略,以优化在LISA手术期间的舒适性.
科学领域:
- 新生儿医学 新生儿医学
- 儿科呼吸系统护理服务
背景情况:
- 较少侵入性表面活性剂 (LISA) 是治疗早产婴儿呼吸困扰综合征的常见方法.
- 在LISA期间,在保持自发呼吸的同时,最佳的疼痛和不适的管理还没有得到很好的定义.
- 临床实践因有限的证据指导前期药物选择而有很大差异.
研究的目的:
- 审查目前关于LISA前期治疗的知识.
- 在LISA手术过程中发现有关疼痛管理的证据缺口.
- 为临床医生提供关于在LISA期间优化患者舒适度的指导.
主要方法:
- 在LISA之前对前期药物治疗的研究进行文献搜索.
- 综合有关药理和非药理干预措施的现有证据.
- 分析当前的临床实践和变化.
主要成果:
- 关于LISA的各种前期治疗选择的有效性和安全性的证据有限.
- 在前期治疗期间维持自发呼吸的具体数据很少.
- 目前对LISA前期治疗的临床方法观察到显著的变化.
结论:
- 需要进行进一步的研究,以建立LISA的最佳前期治疗方案.
- 需要基于证据的指导方针来标准化LISA期间的疼痛管理.
- 解决知识缺口将改善在表面活性剂施用期间的早产婴儿护理.
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