儿科功能性便秘的先发性禁欲阴道:一个系统的审查
Charlotte A L Jonker1, Julia M J van der Zande2, Marc A Benninga3
1Department of Pediatric Gastroenterology and Nutrition, Emma Children's Hospital, Amsterdam UMC, University of Amsterdam, Amsterdam, the Netherlands; Department of Pediatric Surgery, Emma Children's Hospital, Amsterdam UMC, University of Amsterdam, Amsterdam, the Netherlands; Amsterdam UMC, University of Amsterdam, Pediatric Gastroenterology and Nutrition, Pediatric Surgery, Amsterdam Gastroenterology Endocrinology Metabolism, Amsterdam, the Netherlands; Amsterdam Reproduction and Development Research Institute, Amsterdam, the Netherlands.
在患有功能性便秘的儿童中,预先升级的失禁阴囊 (ACE) 手术显示出不同的成功率和并发症率. 为了在儿科护理中标准化ACE治疗指南,需要进一步的研究.
科学领域:
- 儿科手术 儿科手术
- 胃肠病学 胃肠病学
- 临床结果研究研究
背景情况:
- 功能性便秘 (FC) 显著影响儿童的生活质量,尽管保守的治疗.
- 在耐火的儿科FC中,考虑进行先升级性失禁阴囊 (ACE) 手术.
- 本综述评估了儿童功能性便秘的ACE手术结果.
研究的目的:
- 系统地审查在功能性便秘 (FC) 的儿童中进行的前升级性失禁阴道 (ACE) 手术的结果.
主要方法:
- 在2024年3月之前发表的13项研究 (477名儿童) 的系统审查.
- 评估的主要结局:治疗成功 (排便/失禁频率).
- 评估的次要结果:ACE停止,并发症,HRQoL和满意度;证据质量得到评估.
主要成果:
- 在儿科FC中ACE手术的治疗成功率差异很大 (32%-100%).
- 并发症发生率在6%至100%之间,其中0%至34%需要手术干预.
- 报告了与健康相关的生活质量 (HRQoL) 的改善和高患者/家长满意度.
结论:
- 儿童功能性便秘的ACE手术结果显示成功率和并发症率的显著变化.
- 对于儿童ACE手术的标准化定义和治疗指导方针至关重要.
- 进一步的研究应侧重于建立儿童FC管理中的ACE程序的统一协议.
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