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Updated: Jun 10, 2025

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通过非催化域调节APOBEC3GDNA编辑功能的分子机制

Hanjing Yang1, Josue Pacheco1, Kyumin Kim1

  • 1Molecular and Computational Biology, Departments of Biological Sciences, University of Southern California, Los Angeles, CA, 90089, USA.

Nature communications
|October 10, 2024
PubMed
概括

APOBEC3G (阿波蛋白B mRNA编辑酶,催化多类3G) 使用特定的DNA序列来增强其抗病毒编辑. 这项研究揭示了其域如何合作结合DNA,帮助抗病毒防御和癌症突变过程.

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