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Updated: Jun 10, 2025

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细胞内膜网膜蛋白VAPB/ALS8的分泌需要拓逆向

Kosuke Kamemura1, Rio Kozono1, Mizuki Tando1

  • 1Program of Biomedical Science, Graduate School of Integrated Sciences for Life, Hiroshima University, Higashi-Hiroshima, Hiroshima, Japan.

Nature communications
|October 10, 2024
PubMed
概括

与VAMP相关的蛋白质 (VAP) 在分泌过程中经历拓逆转. 矩阵金属蛋白酶分裂VAPMSP域,Mmp1可以恢复ALS8突变的水平,揭示了一种新的分泌途径.

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