对没有痴呆症的人的认知症状进行独立数字干预的系统审查和元分析
Veronica Cabreira1, Tim Wilkinson2, Lisbeth Frostholm3,4
1Centre for Clinical Brain Sciences, University of Edinburgh, Edinburgh, UK. veronica.cabreira@ed.ac.uk.
NPJ digital medicine
|October 10, 2024
概括
在神经精神疾病中,自导数字干预对认知和心理健康显示出小到中等的好处. 虽然对疲劳和生活质量的影响不太确定,但这些数字工具提供了可访问的治疗选择.
科学领域:
- 神经科学是一个神经科学.
- 数字健康数字健康
- 精神病学是一个精神病学.
背景情况:
- 认知症状在神经精神疾病中很常见,对生活质量产生负面影响.
- 自主引导的数字干预提供了可访问和可扩展的解决方案,以弥合研究与实践之间的差距.
- 这些干预措施旨在解决认知缺陷并改善心理健康.
研究的目的:
- 对神经精神疾病中认知症状的自我指导数字干预的有效性进行元分析.
- 评估这些干预措施对心理健康,疲劳,生活质量和日常生活活动的影响.
- 评估不同对照组,持续时间和格式的治疗效果的一致性.
主要方法:
- 一个随机效应的元分析对来自76项试验的数据进行了分析,涉及5214名参与者.
- 该分析比较了数字自导干预与治疗后对照组的结果.
- 关键结果包括认知,心理健康,疲劳,生活质量和日常生活活动.
主要成果:
- 对认知 (g=-0.51) 和心理健康 (g=-0.41) 发现了小到中等的积极影响.
- 观察到对疲劳 (g=-0.27) 和生活质量 (g=-0.17) 的边际显著的积极影响.
- 在日常生活活动中没有发现任何显著的益处.
结论:
- 自主指导的数字跨诊断干预可能为一些神经精神疾病患者提供短期益处.
- 对疲劳和生活质量等非认知结果的影响需要进一步研究.
- 干预的有效性似乎是一致的,无论控制类型,持续时间或交付格式.
相关概念视频
01:30Negative and Cognitive Symptoms of Schizophrenia
44
Negative symptoms of schizophrenia indicate a reduction or absence of typical behaviors and emotional responses found in healthy individuals, while positive symptoms reflect an excess or distortion of normal functioning.
Negative Symptoms
Negative symptoms of schizophrenia manifest as deficits in normal emotional and behavioral functioning, profoundly impacting daily life. Individuals with schizophrenia often display a flat affect, characterized by a near-total absence of emotional expression,...
Negative Symptoms
Negative symptoms of schizophrenia manifest as deficits in normal emotional and behavioral functioning, profoundly impacting daily life. Individuals with schizophrenia often display a flat affect, characterized by a near-total absence of emotional expression,...
44
01:30Cognitive Enhancers: Cholinesterase Inhibitors and NMDA Receptor Antagonists
106
Cognitive enhancers, also known as "smart drugs," are substances used to enhance memory, mental alertness, and concentration. These can be natural or synthetic and improve cognition in conditions like Alzheimer's disease (AD) and other neurodegenerative diseases. Some common examples include caffeine, amphetamines, methylphenidate, modafinil, arecoline, donepezil, vortioxetine, and piracetam. These enhancers work on the principle of synaptic plasticity and altered circuit function.
106
01:30Cognitive Development During Adulthood
65
Cognitive development continues throughout adulthood, undergoing significant shifts across early, middle, and late stages. Individual transition occurs from adolescent idealism to pragmatic and adaptable thinking in early adulthood. During this period, individuals learn to integrate personal beliefs with the recognition that other perspectives are equally valid. Exposure to the complexities of modern society, diverse experiences, and higher education contribute to this adaptive thought process,...
65
01:22Alzheimer's Disease: Treatment
166
Alzheimer's Disease (AD), a neurodegenerative disorder, is pathologically identified by amyloid plaques and neurofibrillary tangles composed of tau protein. AD pharmacotherapy aims to manage cognitive symptoms, delay disease progression, and treat behavioral symptoms. The treatment is primarily symptomatic and palliative, with no definitive disease-modifying therapy available. Cholinesterase inhibitors, including donepezil (Aricept), rivastigmine (Exelon), and galantamine (Razadyne), are...
166
01:25Cognitive Therapy
146
Cognitive therapy, pioneered by Aaron T. Beck in the 1960s, is a structured approach to addressing psychological distress by focusing on the influence of thoughts on emotions and behaviors. All cognitive therapies involve the basic assumption that human beings have control over their feelings, and that how individuals feel about something depends on how they think about it. Unlike psychoanalytic methods that delve into unconscious processes or humanistic approaches emphasizing...
146