针对手术部位感染的抗生素,用于接受正形手术的患者
1Research & Evidence (RF&E), New Delhi, India. vaibhav.sahni@rcsed.net.
Evidence-based dentistry
|October 10, 2024
概括
与短期使用相比,长期的预防性抗生素显著降低了经过整形手术后手术部位感染的风险. 在预防感染方面,一次性术后抗生素治疗方案也比一次性手术前剂量更有效.
科学领域:
- 口腔和牙面部外科手术
- 预防传染病 预防传染病
- 基于证据的医学基于证据的医学.
背景情况:
- 手术部位感染 (SSI) 是骨格内科手术后的一个重要并发症.
- 最佳的抗生素预防方案以尽量减少SSI风险仍在调查中.
研究的目的:
- 为了比较不同预防性抗生素持续时间和时间在削减骨架手术后SSIs的疗效.
主要方法:
- 进行了随机对照试验 (RCT) 的系统审查和元分析.
- 在PubMed,Embase,Web of Science和Scopus进行了搜索.
- 包括11个评价长期与短期或单日与术前抗生素治疗方案的RCT.
主要成果:
- 与短期使用 (1天) 相比,长期预防性抗生素使用 (≥2天) 显著降低了SSI风险.
- 与一次手术前剂量相比,一次性术后抗生素治疗方案显示,SSI风险显著降低.
结论:
- 预防性抗生素的延长持续时间 (2-7天) 优于单日给药,用于减少orthognathic手术后的SSIs.
- 术后单日抗生素预防比单次手术前剂量更有利于SSI的预防.
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