线粒体相关基因的快速进化在平分类关节动物中
Yiyuan Li1, Gregg W C Thomas2,3,4, Stephen Richards5
1State Key Laboratory for Managing Biotic and Chemical Threats to the Quality and Safety of Agro-Products, Key Laboratory of Biotechnology in Plant Protection of Ministry of Agriculture and Rural Affairs, Key Laboratory of Green Plant Protection of Zhejiang Province, Institute of Plant Virology, Ningbo University, Ningbo, 315211, China. lyy0005@gmail.com.
BMC biology
|October 10, 2024
概括
哈普洛迪普洛伊德关节动物在线粒体和核基因中都表现出快速的进化,挑战了人口规模理论. 积极的选择和补偿性变化可能推动了这些进化速率,特别是在蜜蜂和等社会性膜类动物中.
科学领域:
- 进化生物学是进化的生物学.
- 基因组学就是基因组学.
- 分子进化的分子进化.
背景情况:
- 线粒体和核基因对线粒体功能进行合作,特别是在氧化酸化 (OXPHOS) 中.
- 关节动物的线粒体基因表现出不同的进化速率,其中单双双的物种往往表现出加速的进化.
- 快速进化的假设包括由于人口小而导致的遗传漂移或核基因的积极选择/补偿变化.
研究的目的:
- 为了研究进化速率和线粒体和核基因的基因家族周转,在平分类关节动物.
- 测试小有效种群大小驱动单双双体物种快速基因进化这一假设.
- 为了比较线粒体和核基因之间的进化速率,包括与线粒体功能相关的基因.
主要方法:
- 对76种关节动物基因组进行比较基因组学分析.
- 对线粒体和核基因的进化速率的估计.
- 分析线粒体相关基因中的基因家族扩张和收缩.
主要成果:
- 五个哈普洛迪普洛伊德血统显示了与线粒体功能相关的线粒体和核基因的加速进化.
- 与线粒体无关的核基因没有表现出显著的速率差异.
- 蜜蜂和,在 hymenopterans 中,显示了与和黄蜂相比,线粒体和线粒体相关的核基因的分子进化速度更快.
- 在蜜蜂和的线粒体相关基因中观察到基因家族的扩张和收缩.
结论:
- 小种群规模假设被拒绝,因为它是快速进化的主要驱动力.
- 积极选择和补偿性遗传变化的结合可能解释了观察到的进化模式.
- 蜜蜂和的OXPHOS复合体2基因中的高进化速率表明,社会膜动物的进化轨迹是不同的.
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