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天体细胞DLL4-NOTCH1信号通路通过IL-6-STAT3轴促进神经炎症

Pierre Mora1, Margaux Laisné1, Célia Bourguignon1

  • 1Univ. Bordeaux, INSERM, Biology of Cardiovascular Diseases, U1034, 01 avenue de Magellan, Pessac, 33601, France.

Journal of neuroinflammation
|October 10, 2024
PubMed
概括

在星球细胞中阻断Delta-like 4 (DLL4) 会减少神经炎症和血脑屏障损伤. 这一途径对于控制中枢神经系统疾病中的星球细胞反应性至关重要.

关键词:
在 DLL4-NOTCH1 信号通道中.在IL-6-STAT3轴上.神经炎症是一种神经炎症.反应性星球细胞反应性星球细胞.

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